Mutations in Hepatitis C Virus RNAs Conferring Cell Culture Adaptation
نویسندگان
چکیده
منابع مشابه
Clearance of replicating hepatitis C virus replicon RNAs in cell culture by small interfering RNAs.
RNA interference is a cellular process of gene silencing in which small duplexes of RNA specifically target a homologous sequence for cleavage by cellular ribonucleases. The introduction of approximately 22-nt small interfering RNAs (siRNAs) into mammalian cells can specifically silence cellular mRNAs without induction of the nonspecific IFN responses that are activated by longer RNA duplexes. ...
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 2001
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.75.3.1437-1449.2001